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  • Chapter 11 Regulation of Metabolism
    • 11-1 Introduction
    • 11-2 Regulation is a way to respond to a changing environment
    • 11-3 There are common steps in regulation
    • 11-4 Allosteric proteins sense small molecules and change their activity because of them
    • 11-5 Regulation occurs at many different points during gene expression
    • 11-6 Positive and negative regulation involves proteins that bind to DNA
    • 11-7 Attenuation is regulatory mechanism in which translation affects transcription
    • 11-8 Protein activity in prokaryotes is also regulated at the post-transcriptional and translational level
    • 11-9 Expression of the lac operon requires the presence of lactose and the absence of glucose
    • 11-10 The tryptophan operon is controlled by repression, attenuation and feedback inhibition
    • 11-11 Sporulation in Bacillus subtilis is directed by sigma factors and turned on by a phosphorelay system
    • 11-12 Vibrio fischerii senses cell density using a small diffusible molecule that binds to an activator
    • 11-13 Heat-shock gene expression is controlled by σ factors, mRNA secondary structure, and protein stability
    • 11-14 Nitrogen fixation can be controlled by a positive activator, mRNA stability, and enzyme modification
    • 11-15 Summary